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Clinical Experience of Filipino Clinicians on the Use of Bedaquiline for Treating Multi-Drug Resistant Tuberculosis.

Author

Carl Abelardo T. Antonio,
Chelseah Denise H. Torres,
Vivian S. Lofranco,
Aneliese H. Torres,
Stephanie M. Lao,
Amiel Nazer C. Bermudez,
Erwin G. Benedicto

Related Institution

Department of Health Policy and Administration, College of Public Health - University of the Philippines Manila

Department of Applied Social Sciences - The Hong Kong Polytechnic University

College of Public Health - University of the Philippines Manila

Lung Center of the Philippines

Johnson & Johnson (Philippines), Inc.

Department of Epidemiology and Biostatistics, College of Public Health - University of the Philippines Manila

Publication Information

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Project Title
Philippine Journal of Health Research and Development
Title
Philippine Journal of Health Research and Development
Frequency
Quarterly
Publication Date
April-June 2019
Volume
23
Issue
2
Page(s)
20-25

Abstract

BACKGROUND: The Philippines is among countries globally with high multidrug-resistant tuberculosis (MDR-TB) burden. An operations research on Bedaquiline (BDQ), a new drug for MDR-TB, was launched by the Department of Health (DOH) in 2016.


OBJECTIVES: This paper aimed to gather the opinions and first-hand experiences of clinicians in the Philippines regarding BDQ.


METHODS: A facilitated roundtable discussion among nine clinicians included in the operations research on BDQ in the Philippines was conducted in June 2018. Topics covered included: (a) considerations in the use of BDQ, (b) outcomes of patients given BDQ, and (c) perceptions on effectiveness and safety of BDQ. Recordings and field notes from the discussion were subjected to framework analysis.


RESULTS AND CONCLUSION: Participants gave BDQ an overall positive feedback due to the effectiveness, less toxicity, and ease of administration compared to other anti-TB drugs. Issues on BDQ included the novelty of the drug that caused doubts at first use and the limited application of the drug as dictated by the inclusion criteria within the context of the operations research, among others. The significant number of patients lost to follow up and ways to address this challenge were also discussed.

Physical Location

LocationLocation CodeAvailable FormatAvailability
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